This collection contains works by faculty from the Geisel School of Medicine.

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Submissions from 1989

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Guanine Nucleotide-Binding Protein, Alpha i-3, Directly Activates a Cation Channel in Rat Renal Inner Medullary Collecting Duct Cells., Douglas B. Light, Dennis A. Ausiello, and Bruce A. Stanton

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Insertion of the v-Ha-ras Oncogene Induces Differentiation of Calcitonin-Producing Human Small Cell Lung Cancer., Mack Mabry, Toshitaro Nakagawa, Stephen Baylin, Olive Pettengill, George Sorenson, and Barry Nelkin

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Simian Virus 40 Host Range/Helper Function Mutations Cause Multiple Defects in Viral Late Gene Expression., Terryl Stacy, Michele Chamberlain, and Charles N. Cole

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Osteogenesis Imperfecta. The Position of Substitution for Glycine by Cysteine in the Triple Helical Domain of the Pro Alpha 1(I) Chains of Type I Collagen Determines the Clinical Phenotype., Barbra J. Starman, David Eyre, Harry Charbonneau, Maria Harrylock, Mary Ann Weis, Lester Weiss, John M. Graham Jr., and Peter H. Byers

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Linker Insertion Mutants of Simian Virus 40 Large T Antigen that Show Trans-Dominant Interference with Wild-Type Large T Antigen Map to Multiple Sites within the T-antigen Gene., Jiyue Y. Zhu and Charles N. Cole

Submissions from 1988

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Patterns of Polyadenylation Site Selection in Gene Constructs Containing Multiple Polyadenylation Signals., Roger Denome and Charles Cole

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cAMP Antagonizes Interleukin 2-promoted T-cell Cycle Progression at a Discrete Point in Early G1., Kirk W. Johnson, Bruce H. Davis, and Kendall A. Smith

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K+ Efflux in NIH Mouse 3T3 Cells and Transformed Derivatives: Dependence on Extracellular Ca2+ and Phorbol Esters., Martin Lubin

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Watchful Waiting vs. Immediate Transurethral Prostatectomy for Symptomatic Prostatism, Albert G. Mulley Jr, Michael J. Barry, Floyd J. Fowler, and John E. Wennberg

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Dual Mechanisms of Regulation of Type I Iodothyronine 5'-Deiodinase in the Rat Kidney, Liver, and Thyroid Gland. Implications for the Treatment of Hyperthyroidism with Radiographic Contrast Agents., Donald L. St Germain

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Symptom Status and Quality of Life Following Prostatectomy, John E. Wennberg

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Insulin Stimulates the Dephosphorylation and Activation of Acetyl-CoA Carboxylase., Lee A. Witters, Thomas D. Watts, Diana L. Daniels, and Joseph L. Evans

Submissions from 1987

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Molecular Cloning of Human Synovial Cell Collagenase and Selection of a Single Gene from Genomic DNA., Constance E. Brinckerhoff, Peggy L. Ruby, Scott D. Austin, M Elizabeth Fini, and Hillary D. White

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Molecular Cloning and Sequence Analysis of the Plasmodium Falciparum Dihydrofolate Reductase-thymidylate Synthase gene., David J. Bzik, Wu-Bo Li, Toshihiro Horii, and Joseph Inselburg

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In Vitro Reconstitution of Exocytosis from Sea Urchin Egg Plasma Membrane and Isolated Cortical Vesicles, Joseph H. Crabb, Paul A. Modern, and Robert C. Jackson

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Africa's Conservation for Development, Norman Miller and Rodger Yeager

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Detection of Human DNA Polymorphisms with a Simplified Denaturing Gradient Gel Electrophoresis Technique., Walter W. Noll and Mary Collins

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Regulation of Lymphokine Production and Human T Lymphocyte Activation by 1,25-Dihydroxyvitamin D3. Specific Inhibition at the Level of Messenger RNA., William F.C. Rigby, Sylvia Denome, and Michael W. Fanger

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Identification of a Complex Associated with Processing and Polyadenylation in Vitro of Herpes Simplex Virus Type 1 Thymidine Kinase Precursor RNA., Fang Zhang and Charles N. Cole

Submissions from 1986

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Evidence Against the Hypothesis that Prostaglandins are the Vasodepressor Agents of Pregnancy. Serial Studies in Chronically Instrumented, Conscious Rats., Kirk P. Conrad and Mary C. Colpoys

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The Homeo Domain of a Murine Protein Binds 5' to its Own Homeo Box., Abraham Fainsod, Leonard D. Bogarad, Tarmo Ruusala, and Martin Lubin

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Absence of a Structural Basis for Intracellular Recognition and Differential Localization of Nuclear and Plasma Membrane-Associated Forms of Simian Virus 40 Large Tumor Antigen., Donald L. Jarvis, Charles N. Cole, and Janet S. Butel

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Effects of Corn Oil and Benzyl Acetate on Number and Size of Azaserine-Induced Foci in the Pancreas of LEW and F344 Rats, Daniel S. Longnecker, B D. Roebuck, Thomas J. Curphey, Evelyne Lhoste, Charles I. Coon, and Denise MacMillan

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Regulation by Adrenal Corticosteroids of Sodium and Potassium Transport in Loop of Henle and Distal Tubule of Rat Kidney., Bruce A. Stanton

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Fine-Structure Analysis of the Processing and Polyadenylation Region of the Herpes Simplex Virus Type 1 Thymidine Kinase Gene by Using Linker Scanning, Internal Deletion, and Insertion Mutations., Fang Zhang, Roger M. Denome, and Charles N. Cole

Submissions from 1985

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Autoregulation of Collagenase Production by a Protein Synthesized and Secreted by Synovial Fibroblasts: Cellular Mechanism for Control Of Collagen Degradation, Constance Brinckerhoff, Mary Benoit, and William Culp

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Identification of Sequences in the Herpes Simplex Virus Thymidine Kinase Gene Required for Efficient Processing and Polyadenylation., Charles N. Cole and Terryl P. Stacy

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Recognition and Characterization of Stage-Specific Oocyst/Sporozoite Antigens Of Toxoplasma Gondii by Human Antisera., Lloyd H. Kasper and Patricia L. Ware

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Heterogeneity of Clonogenic Cells in Acute Myeloblastic Leukemia., Kert D. Sabbath, Edward D. Ball, Peter Larcom, Roger B. Davis, and James D. Griffin

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Interleukin 2 Regulates its own Receptors., Kendall A. Smith and Doreen A. Cantrell

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Metabolic Effect of 3,3',5'-Triiodothyronine in Cultured Growth Hormone-Producing Rat Pituitary Tumor Cells. Evidence for a Unique Mechanism of Thyroid Hormone Action., D L. St Germain

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Comparative Study of Pituitary-Thyroid Hormone Economy in Fasting and Hypothyroid Rats., Donald L. St Germain and Valerie A. Galton

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Two Separable Functional Domains of Simian Virus 40 Large T Antigen: Carboxyl-terminal Region of Simian Virus 40 Large T Antigen is Required for Efficient Capsid Protein Synthesis., Joanne Tornow, Maryellen Polvino-Bodnar, George Santangelo, and Charles N. Cole

Submissions from 1984

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Gamma Interferon Induces Monocytoid Differentiation in the HL-60 Cell Line., Edward D. Ball, Paul M. Guyre, Li Shen, John M. Glynn, Charles R. Maliszewski, Paul E. Baker, and Michael W. Fanger

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T-cell Growth Factor: Complete Nucleotide Sequence and Organization of the Gene in Normal and Malignant Cells, Nikki Holbrook, Kendall Smith, Albert Fornace, Claudette Comeau, Robert L. Wiskocil, and Gerard R. Crabtree

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Lesions Induced in Rodent Pancreas by Azaserine and other Pancreatic Carcinogens, Daniel S. Longnecker

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Triggering of the T3-Ti antigen-Receptor Complex Results in Clonal T-Cell Proliferation through an Interleukin 2-Dependent Autocrine Pathway., Stefan C. Meuer, Rebecca E. Hussey, Doreen A. Cantrell, James C. Hodgdon, Stuart F. Schlossman, Kendall A. Smith, and Ellis L. Reinherz

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Interferon Gamma Blocks the Growth of Toxoplasma Gondii in Human Fibroblasts by Inducing the Host Cells to Degrade Tryptophan., E. R. Pfefferkorn

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Inhibition of Growth of Toxoplasma Gondii in Cultured Fibroblasts by Human Recombinant Gamma Interferon., E. R. Pfefferkorn and Paul M. Guyre

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Inhibition of T Lymphocyte Mitogenesis by 1,25-Dihydroxyvitamin D3 (Calcitriol)., William F.C. Rigby, Terryl Stacy, and Michael W. Fanger

Submissions from 1983

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Iron and the Liver: Acute Effects of Iron-Loading on Hepatic Heme Synthesis of Rats. Role of Decreased Activity of 5-Aminolevulinate Dehydrase., H L. Bonkowsky, J F. Healey, P R. Sinclair, J F. Sinclair, S I. Shedlofsky, and G H. Elder

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Recombinant Immune Interferon Increases Immunoglobulin G Fc Receptors on Cultured Human Mononuclear Phagocytes, Paul M. Guyre, Peter M. Morganelli, and Renee Miller

Submissions from 1982

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Monoclonal Antibodies to Novel Myeloid Antigens Reveal Human Neutrophil Heterogeneity., Edward D. Ball, Robert F. Graziano, Li Shen, and Michael W. Fanger

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Proteins Antigenically Related to the Human Erythrocyte Glucose Transporter in Normal and Rous Sarcoma Virus-Transformed Chicken Embryo Fibroblasts., Donald W. Salter, Stephen A. Baldwin, Gustav E. Lienhard, and Michael J. Weber

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ColE1 Copy Number Mutants., Londa Schmidt and Joseph Inselburg

Submissions from 1981

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Detergent Extraction of a Presumptive Gating Component from the Voltage-Dependent Sodium Channel, W J. Culp and D T. McKenzie

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Selection and Characterization of ColE1 Plasmid Mutants that Exhibit Altered Stability And Replication., Joseph Inselburg

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Sunbathing Vermilion-crowned Flycatchers Repulse Mates, Lawrence Kilham

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The Other Somalia Part 1 - Illicit Trade and the Hidden Economy, Norman Miller

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Habitat, the New United Nations Initiative in Human Settlements, Norman Miller and James F. Hornig

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T Cell Growth Factor Receptors. Quantitation, Specificity, and Biological Relevance, Richard J. Robb, Allen Munck, and Kendall A. Smith

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Isolation of Plasma Membrane from Human Neutrophils and Determination of Cytochrome b and Quinone Content, Edward P. Sloan, Dana R. Crawford, and Donald L. Schneider

Submissions from 1980

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Functional Relationship between Parts of the Replication Region of Plasmid ColE1., Joseph Inselburg

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Cellular Action of Vasopressin in Medullary Tubules of Mice with Hereditary Nephrogenic Diabetes Insipidus, Brian A. Jackson, Richard M. Edwards, Heinz Valtin, and Thomas P. Dousa

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Rat Dendritic Cells Function as Accessory Cells and Control the Production of a Soluble Factor Required for Mitogenic Responses of T Lymphocytes., Wolfgang E. Klinkert, Jon H. LaBadie, James P. O'Brien, Carl F. Beyer, and William E. Bowers

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China's Revolution in Health, Norman Miller and James C. Strickler

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A Small Area Approach to the Analysis of Health Systems Performance, John E. Wennberg and Alan Gittelsohn

Submissions from 1979

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Kenya Boran Revisited, Norman Miller

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Malawi-Central African Paradox, Norman Miller

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The United Nations Environment Programme, Norman Miller

Submissions from 1977

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Professional Uncertainty and National Priorities for Use of Resources, John E. Wennberg

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A Test of Consumer Contribution to Small Area Variations in Health Care Delivery, John E. Wennberg MD, MPH and Floyd J. Fowler

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The Authors Respond, John E. Wennberg and Alan Gittelsohn

Submissions from 1975

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Health Care Delivery in Maine I: Patterns of Use of Common Surgical Procedures, John E. Wennberg MD, MPH and Alan Gittelsohn

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Health Care Delivery in Maine III: Evaluating the Level of Hospital Performance, John E. Wennberg MD, MPH; Alan Gittelsohn; and Nancy Shapiro

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Health Care Delivery in Maine II: Conditions Explaining Admission to Hospital., John E. Wennberg MD, MPH; Alan Gittelsohn; and David Soule

Submissions from 1974

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Journey in a Forgotten Land - Part 1: Food and Drought in Ethiopian/Kenyan Border Lands, Norman Miller

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Journey in a Forgotten Land- Part 2: Food and Drought: The Broader Picture, Norman Miller

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Vermont Surgery Study, 1969-1971: On the Incidence of Tonsillectomy and Other Common Types of Surgery, John E. Wennberg

Submissions from 1973

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PSRO and the Relationship among Health Need, Elective Surgery and Health Status, John E. Wennberg

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Small Area Variations in Health Care Delivery, John E. Wennberg MD, MPH

Submissions from 1971

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Teaching African Development With Film, Norman Miller

Submissions from 1970

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Political Mobility and the Pedestrian Society, Norman Miller

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Population Review 1970: Kenya, Norman Miller

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The Rural African Political Party: Political Participation in Tanzania, Norman Miller

Submissions from 1969

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Assassination and Political Unity: Kenya, Norman Miller

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The Defeat of a Minister, Norman Miller and Bismark Mwansasu

Submissions from 1968

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The Political Survival of Traditional Leadership, Norman Miller