This collection contains works by faculty from the Geisel School of Medicine.

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Submissions from 2016

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Environmentally Endemic Pseudomonas aeruginosa Strains with Mutations in lasR Are Associated with Increased Disease Severity in Corneal Ulcers, John H. Hammond, Wesley P. Hebert, Amanda Naimie, Kathryn Ray, Rachel D. Van Gelder, Antonio DiGiandomenico, Prajna Lalitha, Muthiah Srinivasan, Nisha R. Acharya, Thomas Lietman, Deborah A. Hogan, and Michael E. Zegans

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A Qualitative Analysis of Virtual Patient Descriptions in Healthcare Education Based on a Systematic Literature Review, Inga Hege, Andrzej A. Kononowicz, Daniel Tolks, and Samuel Edelbring

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Requirements for Pseudomonas aeruginosa Type I-F CRISPR-Cas Adaptation Determined Using a Biofilm Enrichment Assay, Gary E. Heussler, Jon L. Miller, Courtney E. Price, and Alan J. Collins

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Friendly Fire: Biological Functions and Consequences of Chromosomal Targeting by CRISPR-Cas Systems, Gary E. Heussler and George A. O'Toole

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Effect of a Ropy Exopolysaccharide-Producing Bifidobacterium animalis subsp. lactis Strain Orally Administered on DSS-Induced Colitis Mice Model, Claudio Hidalgo-Cantabrana, Francesca Algieri, Alba Rodriguez-Nogales, Teresa Vezza, and Pablo Martínez-Camblor

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Analysis of Lung Microbiota in Bronchoalveolar Lavage, Protected Brush and Sputum Samples from Subjects with Mild-To-Moderate Cystic Fibrosis Lung Disease, Deborah A. Hogan, Sven D. Willger, Emily L. Dolben, Thomas H. Hampton, Bruce A. Stanton, Hilary G. Morrison, Mitchell L. Sogin, Julianna Czum, Alix Ashare, and Michael Tunney

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Global Role of Cyclic AMP Signaling in pH-Dependent Responses in Candida albicans, Jeffrey M. Hollomon, Nora Grahl, Sven D. Willger, Katja Koeppen, and Deborah A. Hogan

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Pyrimidine Pathway-Dependent and -Independent Functions of the Toxoplasma gondii Mitochondrial Dihydroorotate Dehydrogenase, Miryam Andrea Hortua Triana, Daniela Cajiao Herrera, Barbara H. Zimmermann, Barbara A. Fox, and David Bzik

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Temporal variation in the response of tumors to hyperoxia with breathing carbogen and oxygen, Hua-gang Hou, Nadeem Khan, Gai-xin Du, and Sassan Hodge

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Reference-free deconvolution of DNA methylation data and mediation by cell composition effects, E. Andres Houseman, Molly L. Kile, David C. Christiani, Tan A. Ince, Karl T. Kelsey, and Carmen J. Marsit

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Evolutionary Triangulation: Informing Genetic Association Studies with Evolutionary Evidence, Minjun Huang, Britney E. Graham, Ge Zhang, Reed Harder, Nuri Kodaman, Jason H. Moore, Louis Muglia, and Scott M. Williams

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In Vitro Modeling of the Interaction between Human Epithelial Cells and Lymphocytes upon Influenza Infection, Natalia A. Ilyushina and Pete F. Wright

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The prevalence and distribution of the amyloidogenic transthyretin (TTR) V122I allele in Africa, Daniel R. Jacobson, Alice A. Alexander, Clement Tagoe, W T. Garvey, Scott M. Williams, Sara Tishkoff, David Modiano, Sodiomon B. Sirima, Issa Kalidi, Amadou Toure, and Joel M. Buxbaum

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Building from the HIV Response toward Universal Health Coverage, Jonathon Jay, Kent Buse, Marielle Hart, Robert Marten, Scott Kellerman, Morolake Odetoyinbo, Jonathan D. Quick, Timothy Evans, Peter Piot, Mark Dybul, and Agnes Binagwaho

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Blunt abdominal trauma with handlebar injury: A rare cause of traumatic amputation of the appendix associated with acute appendicitis, Amanda Jensen, Reto Baertschiger, Jodi Hackworth, and Fredrick Rescorla

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5-Hydroxymethylcytosine Localizes to Enhancer Elements and is Associated with Survival in Glioblastoma Patients, Kevin C. Johnson, E. Andres Houseman, Jessica E. King, Katharine M. von Herrmann, Camilo E. Fadu, and Brock C. Christensen

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Stress Granules and RNA Processing Bodies are Novel Autoantibody Targets in Systemic Sclerosis, Michael E. Johnson, Andrew V. Grassetti, Jaclyn N. Taroni, Shawn M. Lyons, Devin Schweppe, Jessica K. Gordon, Robert F. Speira, Robert Lafyatis, Paul J. Anderson, Scott A. Gerber, and Michael L. Whitfield

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Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory Neurons, Sarah Katzenell and David A. Leib

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Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2, Jung-Sik Kim, Xiaoyuan He, Bernardo Orr, Gordana Wutz, Victoria Hill, Jan-Michael Peters, Duane A. Compton, and Todd Waldman

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Characterization of RNA Helicase CshA and Its Role in Protecting mRNAs and Small RNAs of Staphylococcus aureus Strain Newman, Samin Kim, Anna-Rita Corvaglia, Stefano Léo, Ambrose Cheung, and Patrice Francois

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Oscillation Phase Locking and Late ERP Components of Intracranial Hippocampal Recordings Correlate to Patient Performance in a Working Memory Task, Jonathan K. Kleen, Markus E. Testorf, David W. Roberts, and Rod C. Scott

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Plasminogen Activator Inhibitor-1 and Diagnosis of the Metabolic Syndrome in a West African Population, Nuri Kodaman, Melinda C. Aldrich, Rafal Sobota, Folkert W. Asselbergs, Nancy J. Brown, Jason H. Moore, and Scott M. Williams

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Cardiovascular Disease Risk Factors in Ghana during the Rural-to-Urban Transition: A Cross-Sectional Study, Nuri Kodaman, Melinda C. Aldrich, Rafal Sobota, Folkert W. Asselbergs, Kwabena A. Poku, Nancy J. Brown, Jason H. Moore, and Scott M. Williams

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A Novel Mechanism of Host-Pathogen Interaction through sRNA in Bacterial Outer Membrane Vesicles, Katja Koeppen, Thomas H. Hampton, Michael Jarek, Maren Scharfe, Scott A. Gerber, Daniel W. Mielcarz, Elora G. Demers, Emily L. Dolben, John H. Hammond, Deborah A. Hogan, and Bruce A. Stanton

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Improving Cell Mixture Deconvolution by Identifying Optimal Dna Methylation Libraries (IDOL), Devin C. Koestler, Meaghan J. Jones, Joseph Usset, Brock C. Christensen, Rondi A. Butler, Michael S. Kobor, John K. Weincke, and Karl T. Kelsey

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Heterogeneity among Isolates Reveals that Fitness in Low Oxygen Correlates with Aspergillus fumigatus Virulence, Caitlin H. Kowalski, Sarah R. Beattie, Kevin K. Fuller, Elizabeth A. McGurk, Yi-Wei Tang, Tobias Hohl, Joshua Obar, and Robert Cramer Jr.

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Medication-Overuse Headache: Differences between Daily and Near-Daily Headache Patients, Abouch V. Krymchantowski, Stewart J. Tepper, Carla Jevoux, and Marcelo M. Valenca

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Physical Activity and Risk of Breast Cancer, Colon Cancer, Diabetes, Ischemic Heart Disease, and Ischemic Stroke Events: Systematic Review and Dose-Response Meta-Analysis for the Global Burden of Disease Study 2013, Hmwe H. Kyu, Victoria F. Bachman, Lily T. Alexander, John E. Mumford, Ashkan Afshin, Kara Estep, J. Lennert Veerman, and Kristen Delwiche

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Immunogenicity and Protective Efficacy of the DAR-901 Booster Vaccine in a Murine Model of Tuberculosis, Timothy Lahey, Dominick Laddy, Krystal Hill, and Jacqueline Schaeffer

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Pilot Study of a Web-Delivered Multicomponent Intervention for Rural Teens with Poorly Controlled Type 1 Diabetes, Amy H. Lansing, Catherine Stanger, Alan Budney, Ann S. Christiano, and Samuel Casella

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Functional Mechanisms Underlying Pleiotropic Risk Alleles at the 19p13.1 Breast–Ovarian Cancer Susceptibility Locus, Kate Lawrenson, Siddhartha Kar, Karen McCue, Karoline Kuchenbaeker, Kyriaki Michailidou, Jonathan Tyrer, Jonathan Beesley, Susan J. Ramus, Qiyuan Li, Melissa K. Delgado, Janet M. Lee, Kristiina Aittomäki, Irene L. Andrulis, Hoda Anton-Culver, Volker Arndt, Banu K. Arun, Brita Arver, Elisa V. Bandera, Monica Barile, Rosa B. Barkardottir, Daniel Barrowdale, Matthias W. Beckmann, Javier Benitez, Andrew Berchuck, Maria Bisogna, Line Bjorge, Carl Blomqvist, William Blot, Natalie Bogdanova, Anders Bojesen, Stig E. Bojesen, Manjeet K. Bolla, Bernardo Bonanni, Anne-Lise Børresen-Dale, Hiltrud Brauch, Paul Brennan, Hermann Brenner, Fionna Bruinsma, Joan Brunet, Shaik Ahmad Buhari, Barbara Burwinkel, Ralf Butzow, Sandra S. Buys, Qiuyin Cai, Trinidad Caldes, Ian Campbell, Rikki Canniotto, Jenny Chang-Claude, Jocelyne Chiquette, Ji-Yeob Choi, Kathleen B.M Claes, GEMO Study Collaborators, Linda S. Cook, Angela Cox, Daniel W. Cramer, Simon S. Cross, Cezary Cybulski, Kamila Czene, Mary B. Daly, Francesca Damiola, Agnieszka Dansonka-Mieszkowska, Hatef Darabi, Joe Dennis, Peter Devilee, Orland Diaz, and Jennifer A. Doherty

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Comparative Genetic Screens in Human Cells Reveal New Regulatory Mechanisms in WNT Signaling, Andres M. Lebensohn, Ramin Dubey, Leif Neitzel, and Ofelia Tacchelly-Benites

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Detecting Gene-Gene Interactions Using a Permutation-Based Random Forest Method, Jing Li, James D. Malley, Angeline S. Andrew, Margaret R. Karagas, and Jason H. Moore

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CircNet: a database of circular RNAs derived from transcriptome sequencing data, Yu-Chen Liu, Jian-Rong Li, Chuan-Hu Sun, Erik Andrews, Rou-Fang Chao, Feng-Mao Lin, Shun-Long Weng, Sheng-Da Hsu, Chieh-Chen Huang, Chao Cheng, Chun-Chi Liu, and Hsien-Da Huang

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Amplification of TLO Mediator Subunit Genes Facilitate Filamentous Growth in Candida Spp., Zhongle Liu, Gary P. Moran, Derek J. Sullivan, Donna M. MacCallum, and Lawrence C. Myers

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VEGFR2 pY949 Signalling Regulates Adherens Junction Integrity and Metastatic Spread, Xiujuan Li, Narendra Padhan, Elisabet O. Sjöström, Francis P. Roche, Chiara Testini, Naoki Honkura, Miguel Sáinz-Jaspeado, Emma Gordon, Katie Bentley, Andrew Philippides, Vladimir Tolmachev, Elisabetta Dejana, Radu V. Stan, Dietmar Vestweber, Kurt Ballmer-Hofer, Christer Betsholtz, Kristian Pietras, Leif Jansson, and Lena Claesson-Welsh

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Development of a Measure of Model Fidelity for Mental Health Crisis Resolution Teams, Brynmor Lloyd-Evans, Gary R. Bond, Torleif Ruud, and Ada Ivanecka

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Streptococcus Pneumoniae Intracranial Abscess and Post-Infectious Vasculitis, Alexandra Lucas, Ko Ko Maung, and Ryan Ratts

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Pharmacy Use by Dual-Eligible Non-Elderly Veterans with Private Healthcare Insurance, Brian C. Lund, Mary E. Charlton, and Alan N. West

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A subset of replication-dependent histone mRNAs are expressed as polyadenylated RNAs in terminally differentiated tissues, Shawn M. Lyons, Clark H. Cunningham, Joshua D. Welch, Beezly Groh, Andrew Y. Guo, Bruce Wei, Michael L. Whitfield, Yue Xiong, and Wiliam Marzluff

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Female Chromosome X Mosaicism is Age-Related and Preferentially Affects the Inactivated X Chromosome, Mitchell J. Machiela, Weiyin Zhou, Eric Karlins, Joshua N. Sampson, Neal D. Freedman, Qi Yang, Belynda Hicks, Casey Dagnall, Christopher Hautman, Kevin B. Jacobs, Christian C. Abnet, Melinda C. Aldrich, Christopher Amos, Laufey T. Amundadottir, Alan A. Arslan, Laura E. Beane-Freeman, Sonja I. Berndt, Amanda Black, William J. Blot, Cathryn H. Bock, Paige M. Bracci, Louise A. Brinton, H Bas Bueno-de-Mesquita, Laurie Burdett, Julie E. Buring, Mary A. Butler, Federico Canzian, Tania Carreon, Kari G. Chaffee, I-Shou Chang, Nilanjan Chatterjee, Chu Chen, Constance Chen, Kexin Chen, Charles C. Chung, Linda S. Cook, Marta Crous Bou, Michael Cullen, Faith G. Davis, Immaculata De Vivo, Ti Ding, and Jennifer Doherty

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Diabetes Pharmacotherapies and Bladder Cancer: A Medicare Epidemiologic Study, Todd A. Mackenzie, Rebecca Zaha, Jeremy Smith, Margaret R. Karagas, and Nancy E. Morden

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Implementing an mHealth System for Substance Use Disorders in Primary Care: A Mixed Methods Study of Clinicians’ Initial Expectations and First Year Experiences, Marie-Louise Mares, David H. Gustafson, Joseph E. Glass, Andrew Quanbeck, Helene McDowell, Fiona McTavish, Amy Atwood, and Lisa Marsch

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Placental Epigenetics in Children’s Environmental Health, Carmen Marsit

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Vitamin D Supplementation to Prevent Acute Respiratory Tract Infections: Systematic Review and Meta-Analysis Of Individual Participant Data, Adrian R. Martineau, David A. Jolliffe, Richard L. Hooper, Lauren Greenberg, John F. Aloia, Peter Bergman, Gal Dubnov-Raz, Susanna Esposito, Davaasambuu Ganmaa, Adit A. Ginde, Emma C. Goodall, Cameron C. Grant, Christopher J. Griffiths, Wim Janssens, Ilkka Laaksi, Semira Manaseki-Holland, David Mauger, David R. Murdoch, Rachel Neale, and Judy R. Rees

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Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation, Vicente Mas, Laura Rodriguez, Eduardo Olmedillas, Olga Cano, Concepcion Palomo, Maria C. Terron, Daniel Luque, Jose A. Melero, and Jason S. McLellan

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Sarcopenia and sarcopenic obesity: do they predict inferior oncologic outcomes after gastrointestinal cancer surgery?, Kimberly L. Mei, John A. Batsis, Jeannine B. Mills, and Stefan D. Holubar

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Data Publication with the Structural Biology Data Grid Supports Live Analysis, Peter A. Meyer, Stephanie Socias, Jason Key, Elizabeth Ransey, Emily C. Tjon, Alejandro Buschiazzo, Ming Lei, Chris Botka, James Withrow, David Neau, Kanagalaghatta Rajashankar, Karen S. Anderson, Chung-I Chang, Walter J. Chazin, Kevin D. Corbett, Michael S. Cosgrove, Sean Crosson, Sirano Dhe-Paganon, Enrico Di Cera, Catherine L. Drennan, Michael J. Eck, Brandt F. Eichman, Qing R. Fan, Adrian R. Ferre-D’Amare, J. Christopher Fromme, K. Christopher Garcia, Rachelle Gaudet, Peng Gong, Stephen C. Harrison, Ekaterina E. Heldwein, Zongchao Jia, Robert J. Keenan, Andrew C. Kruse, Marc Kvansaku, and Jason S. McLellan

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Norman Miller Archive: Africa Research Data and Field Notes, Norman Miller

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MacDonald-Miller Correspondence, Norman Miller and Duncan MacDonald MD

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Artificial Intelligence and Amikacin Exposures Predictive of Outcomes in Multidrug-Resistant Tuberculosis Patients, Chawangwa Modongo, Jotam G. Pasipanodya, Shashikant Srivastava, Nicola Zetola, Scott Williams, Giorgio Sirugo, and Tawanda Gumbo

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Analyzing Clustered Data: Why and How to Account for Multiple Observations Nested within a Study Participant?, Erika L. Moen, Catherine J. Fricano-Kugler, Bryan W. Luikart, and A. James O’Malley

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Assessing the Twinning Model in the Rwandan Human Resources for Health Program: Goal Setting, Satisfaction and Perceived Skill Transfer, Esperance Ndenga, Glorieuse Uwizeye, Dana R. Thomson, Eric Uwitonze, Joel Mubiligi, Bethany L. Hedt-Gauthier, Michael Wilkes, and Agnes Binagwaho

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Human Papillomavirus Infection in Rwanda at the Moment of Implementation of a National HPV Vaccination Programme, Fidele Ngabo, Silvia Franceschi, Iacopo Baussano, M. Chantal Umulisa, Peter Snijders, Anne Uyterlinde, Fulvio Lazzarato, Vanessa Tenet, Maurice Gatera, Agnes Binagwaho, and Gary Clifford

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The Economic Burden Attributable to a Child’s Inpatient Admission for Diarrheal Disease in Rwanda, Fidele Ngabo, Mercy Mvundura, Lauren Gazley, Maurice Gatera, Celse Rugambwa, Eugene Kayonga, Yvette Tuyishme, Jeanne Niyibaho, Jason M. Mwenda, Philippe Donnen, Philippe Lepage, Agnes Binagwaho, and Deborah Atherly

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Effect of Pentavalent Rotavirus Vaccine Introduction on Hospital Admissions for Diarrhoea and Rotavirus in Children in Rwanda: a Time-Series Analysis, Fidele Ngabo, Jacqueline E. Tate, Maurice Gatera, Celse Rugambwa, Philippe Donnen, Philippe Lepage, Jason M. Mwenda, Agnes Binagwaho, and Umesh D. Parashar

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The Vibrio Cholerae Minor Pilin TcpB Initiates Assembly and Retraction of the Toxin-Coregulated Pilus, Dixon Ng, Tony Harn, Tuba Altindal, Subramania Kolappan, Jarrad Marles, Rajan Lala, Ingrid Spielman, Yang Gao, Caitlyn Hauke, and Gabriela Kovacikova

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Social Environment Shapes the Speed of Cooperation, Akihiro Nishi, Nicholas A. Christakis, Anthony M. Evans, A. James O'Malley, and David G. Rand

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Validation of the Kinyarwanda-Version Short-Form Leeds Dyspepsia Questionnaire and Short-Form Nepean Dyspepsia Index to Assess Dyspepsia Prevalence and Quality-of-Life Impact in Rwanda, Arcade Nkurunziza, Vincent Dusabejambo, Kelly Everhart, Steve Bensen, and Tim Walker

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Interallelic Transcriptional Enhancement as an in Vivo Measure of Transvection in Drosophila melanogaster, Geoffrey P. Noble, Patrick J. Dolph, and Surachai Supattapone

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Depression in Visual Impairment Trial (DEPVIT): A Randomized Clinical Trial of Depression Treatments in People With Low Vision, Claire L. Nollett, Nathan Bray, Catey Bunce, Robin J. Casten, Rhiannon T. Edwards, Mark T. Hegel, Sarah Janikoun, Sandra E. Jumbe, Barbara Ryan, and Julia Shearn

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Induction of gut regulatory CD39(+) T cells by teriflunomide protects against EAE, Javier Ochoa-Reparaz, Sara L. Colpitts, Christopher Kircher, and Eli J. Kasper

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Exertional dyspnoea in COPD: the clinical utility of cardiopulmonary exercise testing, Denis E. O'Donnell, Amany F. Elbehairy, Azmy Faisal, Katherine A. Webb, Alberto J. Neder, and Donald A. Mahler

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The Burden of Clostridium Difficile Infection: Estimates of the Incidence of CDI from US Administrative Databases, Margaret A. Olsen, Yinong Young-Xu, Dustin Stwalley, and Ciaran P. Kelly

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Costs of Diagnostic and Preoperative Workup With and Without Breast Mri in Older Women with a Breast Cancer Diagnosis, Tracy Onega, Anna N.A Tosteson, Julie Weiss, Jennifer Alford-Teaster, Rebecca A. Hubbard, Louise M. Henderson, Karla Kerlikowske, Martha E. Goodrich, Cristina O'Donoghue, Karen J. Wernli, Wendy B. DeMartini, and Beth A. Virnig

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Adaptive Resistance to an Inhibitor of Chromosomal Instability in Human Cancer Cells, Bernardo Orr, Lama Talje, Zhexian Liu, and Benjamin H. Kwok

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Biosimilar FSH Preparations- Are They Identical Twins or Just Siblings?, Raoul Orvieto and David B. Seifer

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Regional Implementation of a Pediatric Cardiology Syncope Algorithm Using Standardized Clinical Assessment and Management Plans (SCAMPS) Methodology, Yvonne Paris, Olga H. Toro‐Salazar, Naomi S. Gauthier, Kathleen Rotondo, Lucy Arnold, Rose Hamershock, David E. Saudek, David R. Fulton, Ashley Renaud, Mark E. Alexander, and New England Congenital Cardiology Association (NECCA

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Immune- and Nonimmune-Compartment-Specific Interferon Responses Are Critical Determinants of Herpes Simplex Virus-Induced Generalized Infections and Acute Liver Failure, Zachary M. Parker, Tracy Jo Pasieka, George A. Parker, and David A. Leib

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Meditative Movement as a Treatment for Pulmonary Dysfunction in Flight Attendants Exposed to Second-Hand Cigarette Smoke: Study Protocol for a Randomized Trial, Peter Payne, David Zava, Steven Fiering, and Mardi Crane-Godreau

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In the Information Age, Do Dementia Caregivers Get the Information They Need? Semi-Structured Interviews to Determine Informal Caregivers’ Education Needs, Barriers, and Preferences, Kendra Peterson, Howard Hahn, Amber J. Lee, Catherine A. Madison, and Alireza Atri

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Revisiting photodynamic therapy dosimetry: reductionist & surrogate approaches to facilitate clinical success, Brian Pogue, Jonathon T. Elliot, Stephen Kanick, Scott Davis, and Kimberly Samkoe

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Signaling in Effector Lymphocytes: Insights toward Safer Immunotherapy, Kamalakannan Rajasekaran, Matthew J. Riese, Sridhar Rao, Li Wang, Monica Thakar, Charles Sentman, and Subramaniam Malarkannan

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Incidence and Duration of Type-Specific Human Papillomavirus Infection in High-Risk HPV-Naïve Women: Results from the Control Arm of a Phase II HPV-16/18 Vaccine Trial, Agnihotram V. Ramanakumar, Paulo Naud, Cecilia M. Roteli-Martins, Newton S. de Carvalho, Paola C. de Borba, Julio C. Teixeira, Mark Blatter, Anna-Barbara Moscicki, Diane M. Harper, Barbara Romanowski, Stephen K. Tyring, Brian Ramjattan, Anne Schuind, Gary Dubin, and Eduardo L. Franco

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Lifestyle and Other Factors Explain One-Half of the Variability in the Serum 25-Hydroxyvitamin D Response to Cholecalciferol Supplementation in Healthy Adults, Judy R. Rees, Leila A. Mott, Elizabeth L. Barry, and John A. Baron

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Randomized controlled trials: who fails run-in?, Judy R. Rees, Leila A. Mott, Elizabeth L. Barry, John A. Baron, Jane C. Figueiredo, Douglas J. Robertson, Robert S. Bresalier, and Janet L. Peacock

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Generalized Scaling and the Master Variable for Brownian Magnetic Nanoparticle Dynamics, Daniel B. Reeves, Yipeng Shi, and John B. Weaver

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Comparing desferrioxamine and light fractionation enhancement of ALA-PpIX photodynamic therapy in skin cancer, Ana Luiza Ribeiro de Souza, Kayla Marra, Jason Gunn, Kimberly Samkoe, Stephen Kanick, Scott Davis, M Shane Chapman, Edward Maytin, Tayyaba Hasan, and Brian Pogue

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Phenotypes Associated with Knockouts of Eight Dense Granule Gene Loci (Gra2-9) in Virulent Toxoplasma Gondii, Leah M. Rommereim, Valeria Bellini, Barbara A. Fox, Graciane Pètre, Camille Rak, Bastien Touquet, Delphine Aldebert, Jean-François Dubremetz, Marie-France Cesbron-Delauw, Corinne Mercier, and David J. Bzik

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The Pseudomonas aeruginosa Efflux Pump MexGHI-OpmD Transports a Natural Phenazine that Controls Gene Expression and Biofilm Development, Hassan Sakhtah, Leslie Koyama, Yihan Zhang, Diana K. Morales, Blanche Fields, Alexa Price-Whelan, and Deborah Hogan

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Epithelial Cell Integrin Β1 is Required for Developmental Angiogenesis in the Pituitary Gland, Kathleen M. Scully, Dorota Skowronska-Krawczyk, Michal Krawczyk, Daria Merkurjev, Havilah Taylor, Antonia Livolsi, Jessica Tollkuhn, Radu V. Stan, and Michael G. Rosenfeld

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Throat Swabs and Sputum Culture as Predictors of P. aeruginosa or S. aureus Lung Colonization in Adult Cystic Fibrosis Patients, Darius Seidler, Mary Griffin, Amanda Nymon, Katja Koeppen, and Alix Ashare

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Acetylation of histone H4 lysine 5 and 12 is required for CENP-A deposition into centromeres, Wei-Hao Shang, Tetsuya Hori, Frederick G. Westhorpe, and Kristina M. Godek

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Maximizing the Benefit-Cost Ratio of Anthracyclines in Metastatic Breast Cancer: Case Report of a Patient with a Complete Response to High-Dose Doxorubicin, Kevin Shee, Alan T. Kono, Susan P. D'Anna, Mark A. Seltzer, Xiaoying Lu, Todd W. Miller, and Mary D. Chamberlin

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Constitutively Activated PI3K Accelerates Tumor Initiation and Modifies Histopathology of Breast Cancer, M. R. Sheen, J. D. Marotti, M. J. Allegrezza, M. Rutkowski, J. R. Conejo-Garcia, and S. Fiering

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Methylation of the Glucocorticoid Receptor (NR3C1) in Placenta is Associated with Infant Cry Acoustics, Stephen J. Sheinkopf, Giulia Righi, Carmen J. Marsit, and Barry M. Lester

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Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data, Jianxin Shi, Ju-Hyun Park, Jubao Duan, Sonja T. Berndt, Winton Moy, Kai Yu, Lei Song, William Wheeler, Xing Hua, Debra Silverman, Montserrat Garcia-Closas, Chao Agnes Hsiung, Jonine D. Figueroa, Victoria K. Cortessis, Nuria Malats, and Margaret R. Karagas

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The 40-Residue Insertion in Vibrio Cholerae FadR Facilitates Binding of an Additional Fatty acyl-CoA Ligand, Wei Shi, Gabriela Kovacikova, Wei Lin, Ronald. K. Taylor, Karen Skorupski, and F. Jon Kull

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Expression of Complement and Toll-Like Receptor Pathway Genes is Associated with Malaria Severity in Mali: A Pilot Case Control Study, Rafal S. Sobota, Antoine Dara, Jessica E. Manning, and Amadou Niangaly

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Network-Based Analysis of Genetic Variants Associated with Hippocampal Volume in Alzheimer’S Disease: A Study of Adni Cohorts, Ailin Song, Jingwen Yan, Sungeun Kim, Shannon Leigh Risacher, Aaron K. Wong, Andrew J. Saykin, Li Shen, and Casey S. Greene

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Pharmacotherapy for Chronic Insomnia: A Brief Survey of PCP Attitudes and Preferences, Adam J. Sorscher, Ali A. Siddiqui, Ardis Olson, and Deborah J. Johnson

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A Tobacco Cessation Intervention with Rural, Medically Underserved, Blue- collar Employees: A Quasiexperimental Study, Telisa Stewart, Margaret K. Formica, Anna M. Adachi-Mejia, and Dongliang Wang

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Clinical Genotyping of Non-Small Cell Lung Cancers Using Targeted Next-Generation Sequencing: Utility of Identifying Rare and Co-mutations in Oncogenic Driver Genes, Laura J. Tafe, Kirsten J. Pierce, Jason D. Peterson, Francine de Abreu, Vincent A. Memoli, Candice C. Black, Jason R. Pettus, Jonathan D. Marotti, Edward J. Gutmann, Xiaoying Liu, Keisuke Shirai, Konstantin H. Dragnev, Christopher I. Amos, and Gregory J. Tsongalis

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Cross-Platform Normalization of Microarray and Rna-Seq Data for Machine Learning Applications, Jeffrey A. Thompson, Jie Tan, and Casey S. Greene

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Risk of Medication Overuse Headache across Classes of Treatments for Acute Migraine, Kristian Thorlund, Christina Sun-Edelstein, Eric Druyts, Steve Kanters, Shanil Ebrahim, Rahul Bhambri, Elodie Ramos, Edward Mills, Michel Lanteri-Minet, and Stewart Tepper

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Regulation of Stem Cell Proliferation and Cell Fate Specification by Wingless/Wnt Signaling Gradients Enriched at Adult Intestinal Compartment Boundaries, Ai Tian, Hassina Benchabane, Zhenghan Wang, and Yashi Ahmed

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An FTO Gene Variant Moderates the Association between Parental Restriction and Child BMI, Alison Tovar, Jennifer A. Emond, Erin Hennessy, and Diane Gilbert-Diamond

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Bacterial corneal ulcer associated with common variable immune deficiency, Edmund Tsui, Jie Deng, Andrew N. Siedlecki, and Michael E. Zegans

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Methylation of the Leukocyte Glucocorticoid Receptor Gene Promoter in Adults: Associations with Early Adversity and Depressive, Anxiety and Substance-Use Disorders, A. R. Tyrka, S H. Parade, E S. Welch, K. K. Ridout, L Price, C Marsit, and L Carpenter

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Integrative analysis of cancer genes in a functional interactome, Matthew H. Ung, Chun-Chi Liu, and Chao Cheng