Submissions from 2011
Chromosome Missegregation in Human Cells Arises through Specific Types of Kinetochore–Microtubule Attachment Errors, Sarah L. Thompson and Duane A. Compton
Supplier-Induced Demand for Psychiatric Admissions in Northern New England, Bradley V. Watts, Brian Shiner, Gunnar Klauss, and William B. Weeks
Genetic Determinants of UV-Susceptibility in Non-Melanoma Skin Cancer, Marleen M. Welsh, Margaret R. Karagas, Jacquelyn K. Kuriger, Andres Houseman, Steven K. Spencer, Ann E. Perry, and Heather H. Nelson
Erect Wing Facilitates Context-Dependent Wnt/Wingless Signaling by Recruiting the Cell-Specific Armadillo-TCF Adaptor Earthbound to Chromatin, Nan Xin, Hassina Benchabane, Ai Tian, Kerrie Nguyen, Lindsay Klofas, and Yashi Ahmed
A Lipid-Anchored SNARE Supports Membrane Fusion, Hao Xu, Michael Zick, William T. Wickner, and Youngsoo Jun
Mediator Influences Telomeric Silencing and Cellular Life Span, Xuefeng Zhu, Beidong Liu, Jonas O. P. Carlsten, Jenny Beve, Thomas Nyström, Lawrence C. Myers, and Claes M. Gustafsson
Histone Modifications Influence Mediator Interactions with Chromatin, Xuefeng Zhu, Yongqiang Zhang, Gudrun Bjornsdottir, Zhongle Liu, Amy Quan, Michael Costanzo, Marcela Davila Lopez, Jakub Orzechowski Westholm, Hans Ronne, Charles Boone, Claes M. Gustafsson, and Lawrence C. Myers
Use of Dried-Blood-Spot Samples and In-House Assays To Identify Antiretroviral Drug Resistance in HIV-Infected Children in Resource-Constrained Settings, Carrie Ziemniak, Yohannes Mengistu, Andrea Ruff, Ya-Hui Chen, Leila Khaki, Abubaker Bedri, Birgitte B. Simen, and Paul Palumbo
Crystallization of the Staphylococcus Aureus MazF mRNA Interferase, Valentina Zorzini, Sarah Haesaerts, Niles P. Donegan, and Zhibiao Fu
Submissions from 2010
Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain, Matthew S. Alkaitis, Carlos Solorzano, Russell P. Landry, Daniele Piomelli, Joyce A. DeLeo, and E. Alfonso Romero-Sandoval
Excision Dynamics of Vibrio Pathogenicity Island-2 from Vibrio Cholerae: Role of a Recombination Directionality Factor VefA, Salvador Almagro-Moreno, Michael G. Napolitano, and E. Fidelma Boyd
Salicylic Acid Diminishes Staphylococcus aureus Capsular Polysaccharide Type 5 Expression, Lucia P. Alvarez, Maria S. Barbagelata, Mariana Gordiola, and A. L. Cheung
Pseudomonas aeruginosa Evasion of Phagocytosis Is Mediated by Loss of Swimming Motility and Is Independent of Flagellum Expression, Eyal Amiel, Rustin R. Lovewell, George A. O'Toole, Deborah A. Hogan, and Brent Berwin
Purification, Crystallization and Preliminary X-Ray Diffraction Analysis of Cif, a Virulence Factor Secreted by Pseudomonas Aeruginosa, Christopher D. Bahl, Daniel P. MacEachran, George A. O'Toole, and Dean R. Madden
Crystal Structure of the Cystic Fibrosis Transmembrane Conductance Regulator Inhibitory Factor Cif Reveals Novel Active-Site Features of an Epoxide Hydrolase Virulence Factor, Christopher D. Bahl, Christophe Morisseau, Jennifer M. Bomberger, Bruce A. Stanton, Bruce D. Hammock, George A. O'Toole, and Dean R. Madden
The Cyanobacteria Derived Toxin Beta-N-Methylamino-L-Alanine and Amyotrophic Lateral Sclerosis, Sandra A. Banack, Tracie A. Caller, and Elijah W. Stommel
Optimal Bone Strength and Mineralization Requires the Type 2 Iodothyronine Deiodinase in Osteoblasts, J. H. D. Bassett, Alan Boyde, Peter G. T. Howell, Richard H. Bassett, Thomas M. Galliford, Marta Archanco, Holly Evans, Michelle A. Lawson, Peter Croucher, Donald L. St. Germain, Valerie A. Galton, and Graham R. Williams
Cardiovascular Risk Assessment - From Individual Risk Prediction to Estimation of Global Risk and Change in Risk in the Population, John A. Batsis and Francisco Lopez-Jimenez
Effect of Calcium Supplements on Risk of Myocardial Infarction and Cardiovascular Events: Meta-Analysis, Mark J. Bolland, Allison Avenell, John A. Baron, and A. Grey
ACAT1 Gene Ablation Increases 24(S)-Hydroxycholesterol Content in the Brain and Ameliorates Amyloid Pathology in Mice with AD, Elena Y. Bryleva, Maximillian A. Rogers, Catherine C. Y. Chang, and Floyd Buen
Density Estimation and Adaptive Bandwidths: a Primer for Public Health Practitioners, Heather A. Carlos, Xun Shi, James Sargent, Susanne Tanski, and Ethan M. Berke
CD4 T-Cell Suppression by Cells from Toxoplasma gondii-Infected Retinas Is Mediated by Surface Protein PD-L1, Elizabeth Charles, Sunil Joshi, John D. Ash, and Barbara A. Fox
Physical Interaction Between VIVID and White Collar Complex Regulates Photoadaptation in Neurospora, Chen-Hui H. Chen, Bradley S. DeMay, Amy S. Gladfelter, Jay Dunlap, and Jennifer J. Loros
Breast Cancer DNA Methylation Profiles Are Associated with Tumor Size and Alcohol and Folate Intake, Brock C. Christensen, Karl T. Kelsey, Shichun Zheng, E. Andres Houseman, Carmen J. Marsit, Margaret R. Wrensch, Joseph L. Wiemels, Heather H. Nelson, and Margaret R. Karagas
Deltanp63 Transcriptionally Regulates Atm to Control P53 Serine-15 Phosphorylation., Ashley L. Craig, Jitka Holcakova, Lee E. Finlan, Marta Nekulova, Roman Hrstka, Nuri Gueven, James DiRenzo, Graeme Smith, Ted R. Hupp, and Borivoj Vojtesek
CD277 is a Negative Co-stimulatory Molecule Universally Expressed by Ovarian Cancer Microenvironmental Cells, Juan R. Cubillos-Ruiz, Diana Martinez, Uciane K. Scarlett, Melanie R. Rutkowski, Yolanda C. Nesbeth, Ana L. Camposeco-Jacobs, and Jose R. Conejo-Garcia
Farnesol Induces Hydrogen Peroxide Resistance in Candida albicans Yeast by Inhibiting the Ras-Cyclic AMP Signaling Pathway, Aurélie Deveau, Amy E. Piispanen, Angelyca A. Jackson, and Deborah A. Hogan
Renin-Angiotensin System Activation Correlates with Microvascular Dysfunction in a Prospective Cohort Study of Clinical Sepsis, Kevin C. Doerschug, Angela S. Delsing, Gregory A. Schmidt, and Alix Ashare
Primary Human Mammary Epithelial Cells Endocytose HIV-1 and Facilitate Viral Infection of CD4+ T Lymphocytes, Stephanie M. Dorosko and Ruth I. Connor
Avirulent Uracil Auxotrophs Based on Disruption of Orotidine-5′-Monophosphate Decarboxylase Elicit Protective Immunity to Toxoplasma gondii, Barbara A. Fox and David J. Bzik
Genetic and Molecular Characterization of a Cryptochrome from the Filamentous Fungus Neurospora Crassa, Allan C. Froehlich, Chen-Hui Chen, William J. Belden, and Cornelia Madeti
Anti-HIV Activity in Cervical-Vaginal Secretions from HIV-Positive and -Negative Women Correlate with Innate Antimicrobial Levels and IgG Antibodies, Mimi Ghosh, John V. Fahey, Zheng Shen, Timothy Lahey, Susan Cu-Uvin, Zhijin Wu, Kenneth Mayer, Peter F. Wright, John C. Kappes, Christina Ochsenbauer, and Charles R. Wira
Progressive Changes in Microglia and Macrophages in Spinal Cord and Peripheral Nerve in the Transgenic Rat Model of Amyotrophic Lateral Sclerosis, David J. Graber, William F. Hickey, and Brent T. Harris
microRNAs Reveal the Interrelationships of Hagfish, Lampreys, and Gnathostomes and the Nature of the Ancestral Vertebrate, Alysha M. Heimberg, Richard Cowper-Sal{middle dot}lari, Marie Semon, Philip C. J. Donoghue, and Kevin J. Peterson
HOPS Initiates Vacuole Docking by Tethering Membranes Before Trans-SNARE Complex Assembly, Christopher M. Hickey and William Wickner
In-Home Coal and Wood Use and Lung Cancer Risk: A Pooled Analysis of the International Lung Cancer Consortium, H Dean Hosgood, Paolo Boffetta, Sander Greenland, and Yuan-Chin Amy Lee
The Climatic Niche Diversity of Malagasy Primates: A Phylogenetic Perspective, Jason M. Kamilar and Kathleen M. Muldoon
Aminoglycoside Resistance of Pseudomonas Aeruginosa Biofilms Modulated by Extracellular Polysaccharide, Wajiha Khan, Steve P. Bernier, Sherry L. Kuchma, John H. Hammond, Fariha Hasan, and George A. O'Toole
Functional Characterization of MAT1-1-Specific Mating-Type Genes in the Homothallic Ascomycete Sordaria Macrospora Provides New Insights into Essential and Nonessential Sexual Regulators, V. Klix, M. Nowrousian, C. Ringelberg, and J. J. Loros
The LysR-Type Virulence Activator AphB Regulates the Expression of Genes in Vibrio Cholerae in Response to Low pH and Anaerobiosis, Gabriela Kovacikova, Wei Lin, and Karen Skorupski
Warfarin Genotyping Using Three Different Platforms, Joel A. Lefferts, Mary C. Schwab, Uday B. Dandamudi, Hong-Kee Lee, Lionel D. Lewis, and Gregory J. Tsongalis
Requirement for Golgi-Localized PI(4)P in Fusion of COPII Vesicles with Golgi Compartments, Andres Lorente-Rodriguez and Charles Barlowe
Deficient Cd40-Traf6 Signaling in Leukocytes Prevents Atherosclerosis by Skewing the Immune Response Toward an Antiinflammatory Profile, Esther Lutgens, Dirk Lievens, Linda Beckers, Erwin Wijnands, Oliver Soehnlein, Alma Zernecke, Tom Seijkens, David Engel, Jack Cleutjens, Anna M. Keller, Shalin H. Naike, Louis Boon, Hafid Ait Oufella, Ziad Mallat, Cory L. Ahonen, Randolph J. Noelle, Menno P. de Winther, Mat J. Daemen, Erik A. Biessen, and Christian Weber
Role of FlgT in Anchoring the Flagellum of Vibrio cholerae, Raquel M. Martinez, Brooke A. Jude, Thomas J. Kirn, Karen Skorupski, and Ronald k. Taylor
Interferon Regulatory Factor 3-Dependent Pathways Are Critical for Control of Herpes Simplex Virus Type 1 Central Nervous System Infection, Vineet D. Menachery, Tracy J. Pasieka, and David A. Leib
Mononucleosis and Antigen-Driven T Cell Responses Have Different Requirements for Interleukin-2 Signaling in Murine Gammaherpesvirus Infection, Michael Molloy, Weijun Zhang, and Edward Usherwood
Bone Marrow Stromal Cells Use Tgf-Β to Suppress Allergic Responses in a Mouse Model of Ragweed-Induced Asthma, K. Nemeth, A. Keane-Myers, J. M. Brown, D. D. Metcalfe, and J. D. Gorham
Harnessing the Effect of Adoptively Transferred Tumor-Reactive T Cells on Endogenous (Host-Derived) Antitumor Immunity, Yolanda Nesbeth and Jose R. Conejo-Garcia
Antipsychotic Adherence, Switching, and Health Care Service Utilization among Medicaid Recipients with Schizophrenia, Douglas L. Noordsy, Glenn A. Phillips, Daniel E. Ball, and Walter T. Linde-Zwirble
CD4+ T Cell Regulation of CD25 Expression Controls Development of Short-Lived Effector CD8+ T Cells in Primary and Secondary Responses, Joshua J. Obar, Michael J. Molloy, Evan R. Jellison, Thomas A. Stoklasek, Weijun Zhang, Edward J. Usherwood, and Leo Lefrançois
Uterine Epithelial Cell Regulation of DC-SIGN Expression Inhibits Transmitted/Founder HIV-1 Trans Infection by Immature Dendritic Cells, Daniel O. Ochiel, Christina Ochsenbauer, John C. Kappes, Mimi Ghosh, John V. Fahey, and Charles R. Wira
Smart Density: A More Accurate Method of Measuring Rural Residential Density for Health-related Research, Peter M. Owens, Linda Titus-Ernstoff, Lucinda Gibson, Michael L. Beach, Sandy Beauregard, and Madeline A. Dalton
CARHSP1 Is Required for Effective Tumor Necrosis Factor Alpha mRNA Stabilization and Localizes to Processing Bodies and Exosomes, Jason R. Pfeiffer, Bethany L. McAvoy, Ryan E. Fecteau, Kristen M. Deleault, and Seth A. Brooks
Imaging Targeted-Agent Binding In Vivo with Two Probes, Brian W. Pogue, Kimberley S. Samkoe, Shannon Hextrum, Julia A. O'Hara, Michael Jermyn, Subhadra Srinivasan, and Tayyaba Hasan
ERK1/2-Akt1 Crosstalk Regulates Arteriogenesis in Mice and Zebrafish, Bin Ren, Yong Deng, Arpita Mukhopadhyay, Anthony A. Lanahan, Zhen W. Zhuang, Karen L. Moodie, Mary Jo Mulligan-Kehoe, Tatiana V. Byzova, Randall T. Peterson, and Michael Simons
IL-28 Supplants Requirement for Treg Cells in Protein σ1-Mediated Protection against Murine Experimental Autoimmune Encephalomyelitis (EAE), Agnieszka Rynda, Massimo Maddaloni, Javier Ochoa-Repáraz, Gayle Callis, and David W. Pascual
Requirements for Transitional Endoplasmic Reticulum Site Structure and Function in Saccharomyces cerevisiae, Polina Shindiapina and Charles Barlowe
Engagement in Mental Health Treatment among Veterans Returning from Iraq, Tracy Stecker, John Fortney, Francis Hamilton, Cathy D. Sherbourne, and Icek Ajzen
H-NS Binding and Repression of the ctx Promoter in Vibrio cholerae, Emily A. Stonehouse, Robin R. Hulbert, Melinda B. Nye, Karen Skorupski, and Ronald K. Taylor
The Staphylococcus-Specific Gene rsr Represses agr and Virulence in Staphylococcus aureus, Sandeep Tamber, Dindo Reyes, Niles P. Donegan, Joseph D. Schwartzman, Ambrose L. Cheung, and Guido Memmi
Role of PknB Kinase in Antibiotic Resistance and Virulence in Community-Acquired Methicillin-Resistant Staphylococcus aureus Strain USA300, S. Tamber, J. Schwartzman, and A. L. Cheung
Proliferation of Aneuploid Human Cells is Limited by a p53-Dependent Mechanism, Sarah L. Thompson and Duane A. Compton
Cortisol Exerts Bi-Phasic Regulation of Inflammation in Humans, Mark P. Yeager, Patricia Pioli, and Paul M. Guyre
Submissions from 2009
Uncoupling Scavenger Receptor A-Mediated Phagocytosis of Bacteria from Endotoxic Shock Resistance, Eyal Amiel, Julie L. Acker, Ryan M. Collins, and Brent Berwin
Multifactor Dimensionality Reduction Analysis Identifies Specific Nucleotide Patterns Promoting Genetic Polymorphisms, Eric Arehart, Scott Gleim, Bill White, John Hwa, and Jason H. Moore
Disruption of Histone Modification and CARM1 Recruitment by Arsenic Represses Transcription at Glucocorticoid Receptor-Regulated Promoters, Fiona D. Barr, Lori J. Krohmer, Joshua W. Hamilton, and Lynn A. Sheldon
Real Time Pcr Detection of the Pi*Z and Pi*S Mutations Associated with Alpha-1 Antitrypsin Deficiency, Claudine L. Bartels, Angela L. Marchetti, W. Edward Highsmith, and Gregory J. Tsongalis
Distinction of the Memory B Cell Response to Cognate Antigen Versus Bystander Inflammatory Signals, Micah J. Benson, Raul Elgueta, William Schpero, Michael Molloy, Weijun Zhang, Edward Usherwood, and Randolph J. Noelle
mTORC1 Hyperactivity Inhibits Serum Deprivation-Induced Apoptosis via Increased Hexokinase II and GLUT1 Expression, Sustained Mcl-1 Expression, and Glycogen Synthase Kinase 3β Inhibition, Prashanth T. Bhaskar, Veronique Nogueira, Krushna C. Patra, Sang-Min Jeon, Youngkyu Park, R. Brooks Robey, and Nissim Hay
U2OS Cells Lacking Chk1 Undergo Aberrant Mitosis and Fail to Activate the Spindle Checkpoint, Laura Carrassa, Yolanda Sanchez, Eugenio Erba, and Giovanna Damia
Aging and Environmental Exposures Alter Tissue-Specific DNA Methylation Dependent upon CpG Island Context, Brock C. Christensen, E Andres Houseman, Carmen J. Marsit, Shichun Zheng, Margaret R. Wrensch, Joseph L. Wiemels, Heather H. Nelson, and Margaret R. Karagas
Polyethylenimine-Based SiRNA Nanocomplexes Reprogram Tumor-Associated Dendritic Cells via TLR5 to Elicit Therapeutic Antitumor Immunity, Juan R. Cubillos-Ruiz, Xavier Engle, Uciane K. Scarlett, and Diana Martinez
A Truncation Mutation in TBC1D4 in a Family with Acanthosis Nigricans and Postprandial Hyperinsulinemia, Satya Dash, Hiroyuki Sano, Justin J. Rochford, and Robert K. Semple
Statistical Hypothesis Testing for Postreconstructed and Postregistered Medical Images, Eugene Demidenko
Regulation of the mazEF Toxin-Antitoxin Module in Staphylococcus aureus and Its Impact on sigB Expression, Niles P. Donegan and Ambrose L. Cheung
Proteolytic Regulation of Toxin-Antitoxin Systems by ClpPC in Staphylococcus aureus, Niles P. Donegan, Earl T. Thompson, Zhibiao Fu, and Ambrose L. Cheung
Suppression of RhoG activity is Mediated by a Syndecan 4–Synectin–RhoGDI1 Complex and is Reversed by PKCα in a Rac1 Activation Pathway, Arye Elfenbein, John M. Rhodes, Julia Meller, Martin A. Schwartz, Michiyuki Matsuda, and Michael Simons
Efficient Gene Replacements in Toxoplasma gondii Strains Deficient for Nonhomologous End Joining, Barbara A. Fox, Jessica G. Ristuccia, Jason P. Gigley, and David J. Bzik
Overexpression of MazFSa in Staphylococcus aureus Induces Bacteriostasis by Selectively Targeting mRNAs for Cleavage, Zhibiao Fu, Sandeep Tamber, Guido Memmi, Niles P. Donegan, and Ambrose L. Cheung
Automated Identification of Tumor Microscopic Morphology based on Macroscopically Measured Scatter Signatures, Pilar Beatriz Garcia-Allende, Venkataramanan Krishnaswamy, P Jack Hoopes, Kimberley S. Samkoe, Olga M. Conde, and Brian W. Pogue
Microbial NAD Metabolism: Lessons from Comparative Genomics, Francesca Gazzaniga, Rebecca Stebbins, Sheila Z. Chang, Mark A. McPeek, and Charles Brenner
Long-Term Immunity to Lethal Acute or Chronic Type II Toxoplasma gondii Infection Is Effectively Induced in Genetically Susceptible C57BL/6 Mice by Immunization with an Attenuated Type I Vaccine Strain, Jason P. Gigley, Barbara A. Fox, and David J. Bzik
Spatially Uniform ReliefF (SURF) for Computationally-Efficient Filtering of Gene-Gene Interactions, Casey S. Greene, Nadia M. Penrod, Jeff Kiralis, and Jason H. Moore
Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture, Casey S. Greene, Nadia M. Penrod, Scott M. Williams, and Jason H. Moore
Decreased Replication Origin Activity in Temporal Transition Regions, Zeqiang Guan, Christina M. Hughes, Settapong Kosiyatrakul, Paolo Norio, Ranjan Sen, and Steven Fiering
Lung Cancer in a U.S. Population with Low to Moderate Arsenic Exposure, Julia Heck
Integral Membrane Proteins Brr6 and Apq12 Link Assembly of the Nuclear Pore Complex to Lipid Homeostasis in the Endoplasmic Reticulum, Christine A. Hodge, Vineet Choudhary, Michael J. Wolyniak, John J. Scarcelli, Roger Schneiter, and Charles N. Cole
A Barrier to Exclusive Breastfeeding for Wic Enrollees: Limited Use of Exclusive Breastfeeding Food Package for Mothers, Alison Volpe Holmes, Nancy P. Chin, Jeffrey Kaczorowski, and Cindy R. Howard
Minimum Criteria for DNA Damage-Induced Phase Advances in Circadian Rhythms, Christian I. Hong, Judit Zámborszky, and Attila Csikász-Nagy
Ras Activity Levels Control the Development of Pancreatic Diseases, Baoan Ji, Lilian Tsou, Huamin Wang, Sebastian Gaiser, David Chang, Jaroslaw Daniluk, Yan Bi, Tobias Grote, Daniel Longnecker, and Craig Logsdon
Kinetics and Phenotype of Vaccine-Induced CD8+ T-Cell Responses to Toxoplasma gondii, Kimberly A. Jordan, Emma H. Wilson, Elia D. Tait, Barbara A. Fox, David S. Roos, and David J. Bzik
Levels of the Secreted Vibrio cholerae Attachment Factor GbpA Are Modulated by Quorum-Sensing-Induced Proteolysis, Brooke A. Jude, Raquel M. Martinez, Karen Skorupski, and Ronald K. Taylor
Development and Validation of an Index of Musculoskeletal Functional Limitations, Jeffrey N. Katz, Elizabeth A. Wright, John A. Baron, and Elena Losina
Imaging of Glioma Tumor with Endogenous Fluorescence Tomography, Dax S. Kepshire, Summer L. Gibbs-Strauss, Julia A. O'Hara, Michael Hutchins, Niculae Mincu, Frederic Leblond, Mario Khayat, Hamid Dehghani, Subhadra Srinivasan, and Brian W. Pogue
Low-Dose Arsenic Compromises the Immune Response to Influenza A Infection in Vivo, Courtney D. Kozul, Kenneth H. Ely, Richard I. Enelow, and Joshua W. Hamilton
Chronic Exposure to Arsenic in the Drinking Water Alters the Expression of Immune Response Genes in Mouse Lung, Courtney D. Kozul, Thomas H. Hampton, Jennifer C. Davey, Julie A. Gosse, Athena P. Nomikos, Phillip L. Eisenhauer, Daniel J. Weiss, Jessica E. Thorpe, Michael A. Ihnat, and Joshua W. Hamilton
Genetic Mapping of Secretion and Functional Determinants of the Vibrio cholerae TcpF Colonization Factor, Shelly J. Krebs, Thomas J. Kirn, and Ronald K. Taylor
Mast Cell–Derived Particles Deliver Peripheral Signals to Remote Lymph Nodes, Christian A. Kunder, Ashley L. St. John, Guojie Li, Kam W. Leong, Brent Berwin, Herman F. Staats, and Soman N. Abraham
Lymphocyte Proliferation to Mycobacterial Antigens is Detectable Across a Spectrum of HIV-Associated Tuberculosis, Timothy Lahey, Mecky Matee, Lillian Mtei, Muhammad Bakari, Kisali Pallangyo, and C Fordham von Reyn
Interconnections between Sigma B, agr, and Proteolytic Activity in Staphylococcus aureus Biofilm Maturation, Katherine J. Lauderdale, Blaise R. Boles, Ambrose L. Cheung, and Alexander R. Horswill