Submissions from 2004
Synthetic Fragments of Vibrio cholerae O1 Inaba O-Specific Polysaccharide Bound to a Protein Carrier Are Immunogenic in Mice but Do Not Induce Protective Antibodies, Michael D. Meeks, Rina Saksena, Xingquan Ma, Terri K. Wade, Ronald K. Taylor, Pavol Kováč, and William F. Wade
Resolution of Organelle Docking and Fusion Kinetics in a Cell-Free Assay, Alexey J. Merz and William T. Wickner
Trans-SNARE Interactions Elicit Ca2+ Efflux from the Yeast Vacuole Lumen, Alexey J. Merz and William T. Wickner
A Novel Triterpenoid Induces Transforming Growth Factor β Production by Intraepithelial Lymphocytes to Prevent Ileitis, Laurie A. Minns, Dominique Buzoni-gatel, Kenneth H. Ely, Nicolas Rachinel, Souphalone Luangsay, and Lloyd H. Kasper
The Kidney-Specific WNK1 Isoform is Induced by Aldosterone and Stimulates Epithelial Sodium Channel-Mediated Na+ Transport, Anikó Naray-Fejes-Toth, Peter M. Snyder, and Géza Fejes-Toth
Hearing Loss and Retarded Cochlear Development in Mice Lacking Type 2 Iodothyronine Deiodinase, Lily Ng, Richard J. Goodyear, Chad A. Woods, and Mark J. Schneider
T-Cell Responses to the M3 Immune Evasion Protein of Murid Gammaherpesvirus 68 Are Partially Protective and Induced with Lytic Antigen Kinetics, Joshua J. Obar, Douglas C. Donovan, Sarah G. Crist, Ondine Silvia, James P. Stewart, and Edward J. Usherwood
BCMA is Essential for the Survival of Long-lived Bone Marrow Plasma Cells, Brian P. O'Connor, Vanitha S. Raman, Loren D. Erickson, W. James Cook, Lehn K. Weaver, Cory Ahonen, Ling-Li Lin, George Mantchev, Richard J. Bram, and Randolph J. Noelle
Binding Between the Niemann–Pick C1 Protein and a Photoactivatable Cholesterol Analog Requires a Functional Sterol-Sensing Domain, Nobutaka Ohgami, Dennis C. Ko, Matthew Thomas, Matthew P. Scott, Catherine C. Y. Chang, and Ta-Yuan Chang
Endogenous NO Regulates Superoxide Production at Low Oxygen Concentrations by Modifying the Redox State of Cytochrome c Oxidase, Miriam Palacios-Callender, Marisol Quintero, Veronica S. Hollis, Roger J. Springett, and Salvador Moncada
The C. Elegans Heterochronic Gene lin-46 Affects Developmental Timing at Two Larval Stages and Encodes a Relative of the Scaffolding Protein Gephyrin, A. S.-R. Pepper, Jill E. McCane, Kevin Kemper, Dennis Au Yeung, Rosalind C. Lee, Victor Ambros, and Eric G. Moss
Differential Expression of Toll-Like Receptors 2 and 4 in Tissues of the Human Female Reproductive Tract, Patricia A. Pioli, Eyal Amiel, Todd M. Schaefer, John E. Connolly, Charles R. Wira, and Paul M. Guyre
Characterization of Hemoglobin, Water, and NIR Scattering in Breast Tissue: Analysis of Intersubject Variability and Menstrual Cycle Changes, Brian W. Pogue, Shudong Jiang, Hamid Dehghani, Christine Kogel, Sandra Soho, Subhadra Srinivasan, Xiaomei Song, Tor D. Tosteson, Steven P. Poplack, and Keith D. Paulsen
The Nuclear Pore Complex and the DEAD Box Protein Rat8p/Dbp5p Have Nonessential Features Which Appear To Facilitate mRNA Export following Heat Shock, Christiane Rollenhagen, Christine A. Hodge, and Charles N. Cole
Inactivation of a Bacterial Virulence Pheromone by Phagocyte-Derived Oxidants: New Role for the NADPH Oxidase in Host Defense, Jacob M. Rothfork, Graham S. Timmins, Michael N. Harris, Xian Chen, Aldons J. Lusis, Michael Otto, Ambrose L. Cheung, and Hattie D. Gresham
Expression Profiling of Mammalian Micrornas Uncovers a Subset of Brain-Expressed Micrornas with Possible Roles in Murine and Human Neuronal Differentiation, Lorenzo F. Sempere, Sarah Freemantle, Ian Pitha-Rowe, Eric Moss, Ethan Dmitrovsky, and Victor Ambros
The Tumor Suppressor LKB1 Kinase Directly Activates AMP-Activated Kinase and Regulates Apoptosis in Response to Energy Stress, Reuben J. Shaw, Monica Kosmatka, Nabeel Bardeesy, Rebecca L. Hurley, Lee A. Witters, Ronald A. DePinho, and Lewis C. Cantley
PV1 is a Key Structural Component for the Formation of the Stomatal and Fenestral Diaphragms, Radu V. Stan, Eugene Tkachenko, and Ingrid R. Niesman
A Vibrio cholerae Classical TcpA Amino Acid Sequence Induces Protective Antibody That Binds an Area Hypothesized To Be Important for Toxin-Coregulated Pilus Structure, Ronald K. Taylor, Thomas J. Kirn, Michael D. Meeks, Terri K. Wade, and William F. Wade
Fibroblast growth factor 2 endocytosis in endothelial cells proceed via syndecan-4-dependent activation of Rac1 and a Cdc42-dependent macropinocytic pathway, Eugene Tkachenko, Esther Lutgens, Radu-Virgil Stan, and Michael Simons
Use of Hospitals, Physician Visits, and Hospice Care during Last Six Months of Life among Cohorts Loyal to Highly Respected Hospitals in the United States, J. E. Wennberg, Elliot S. Fisher, Therese A. Stukel, and Jonathan S. Skinner
SLBP is Associated with Histone mRNA on Polyribosomes as a Component of the Histone mRNP, Michael L. Whitfield, Handan Kaygun, Judith A. Erkmann, W. H. Davin Townley-Tilson, Zbig Dominski, and William F. Marzluff
Impacts of sarA and agr in Staphylococcus aureus Strain Newman on Fibronectin-Binding Protein A Gene Expression and Fibronectin Adherence Capacity In Vitro and in Experimental Infective Endocarditis, Yan-Qiong Xiong, Arnold S. Bayer, Michael R. Yeaman, Willem van Wamel, Adhar C. Manna, and Ambrose L. Cheung
Submissions from 2003
Genomic and Proteomic Profiling of Responses to Toxic Metals in Human Lung Cells, Angeline S. Andrew, Amy J. Warren, Aaron Barchowsky, Kaili A. Temple, Linda Klei, Nicole V. Soucy, Kimberly A. O'Hara, and Joshua W. Hamilton
IL-23 Produced by CNS-Resident Cells Controls T Cell Encephalitogenicity During the Effector Phase of Experimental Autoimmune Encephalomyelitis, Burkhard Becher, Brigit G. Durell, and Randolph J. Noelle
Environmental Estrogens Alter Early Development in Xenopus laevis, Cassandra L. Bevan, Donna M. Porter, Anita Prasad, Marthe J. Howard, and Leslie P. Henderson
Probucol Prevents Early Coronary Heart Disease and Death in the High-Density Lipoprotein Receptor SR-BI/Apolipoprotein E Double Knockout Mouse, Anne Braun, Songwen Zhang, Helena E. Miettinen, Shamsah Ebrahim, Teresa M. Holm, Eliza Vasile, and Mark J. Post
Alpha-Toxin Is Required for Biofilm Formation by Staphylococcus aureus, Nicky C. Caiazza and George A. O'Toole
Rhamnolipid Surfactant Production Affects Biofilm Architecture in Pseudomonas aeruginosa PAO1, Mary E. Davey, Nicky C. Caiazza, and George A. O'Toole
The Triterpenoid CDDO Inhibits Expression of Matrix Metalloproteinase-1, Matrix Metalloproteinase-13 and Bcl-3 in Primary Human Chondrocytes, Sarah Elliott, Ezra Hays, Michael Mayor, Michael Sporn, and Matthew P. Vincenti
A Genetic Lesion that Arrests Plasma Cell Homing to the Bone Marrow, Loren D. Erickson, Ling-Li Lin, Biyan Duan, Laurence Morel, and Randolph J. Noelle
Regulation and Localization of Endogenous Human Tristetraprolin, Anna-Marie Fairhurst, John E. Connolly, Katharine A Hintz, and Nicolas J Goulding
Rpb4p, a Subunit of RNA Polymerase II, Mediates mRNA Export during Stress, Marganit Farago, Tal Nahari, Christopher Hammel, Charles N. Cole, and Mordechai Choder
Rhythmic Binding of a WHITE COLLAR-Containing Complex to the Frequency Promoter is Inhibited by FREQUENCY, Allan C. Froehlich, Jennifer J. Loros, and Jay C. Dunlap
Use of In Vivo-Induced Antigen Technology (IVIAT) to Identify Genes Uniquely Expressed During Human Infection with Vibrio Cholerae, Long Hang, Manohar John, Muhammad Asaduzzaman, Emily A. Bridges, Cecily Vanderspurt, Thomas J. Kirn, and Ronald K. Taylor
A Role for Yip1p in COPII Vesicle Biogenesis, Matthew Heidtman, Catherine Z. Chen, Ruth N. Collins, and Charles Barlowe
Promoters of the Murine Embryonic β-Like Globin Genes Ey and βh1 Do Not Compete for Interaction with the β-globin Locus Control Region, Xiao Hu, Michael Bulger, Julia N. Roach, Susan K. Eszterhas, Emmanuel Olivier, Eric Bouhassira, Mark Groudine, and Steven Fiering
Vam10p Defines a Sec18p-Independent step of Priming that Allows Yeast Vacuole Tethering, Masashi Kato and William Wickner
Minus-End Capture of Preformed Kinetochore Fibers Contributes to Spindle Morphogenesis, Alexey Khodjakov, Lily Copenagle, Michael B. Gordon, Duane A. Compton, and Tarun M. Kapoor
The Virulence Activator AphA Links Quorum Sensing to Pathogenesis and Physiology in Vibrio cholerae by Repressing the Expression of a Penicillin Amidase Gene on the Small Chromosome, Gabriela Kovacikova, Wei Lin, and Karen Skorupski
Salicylic Acid Attenuates Virulence in Endovascular Infections by Targeting Global Regulatory Pathways in Staphylococcus Aureus, Leon Iri Kupferwasser, Michael R. Yeaman, Cynthia C. Nast, Deborah Kupferwasser, Yan-Qiong Xiong, Marco Palma, Ambrose L. Cheung, and Arnold S. Bayer
A Functional Relationship between NuMA and Kid is Involved in Both Spindle Organization and Chromosome Alignment in Vertebrate Cells, Aime A. Levesque, Louisa Howard, Michael B. Gordon, and Duane A. Compton
Human Acyl-Coenzyme A:Cholesterol Acyltransferase Expressed in Chinese Hamster Ovary Cells: Membrane Topology and Active Site Location, Song Lin, Xiaohui Lu, Catherine C.Y. Chang, and Ta-Yuan Chang
Crystal Structure of the SarS Protein from Staphylococcus aureus, Ronggui Li, Adhar C. Manna, Shaodong Dai, Ambrose L. Cheung, and Gongyi Zhang
CCR5 Mediates Specific Migration of Toxoplasma Gondii—Primed CD8+ Lymphocytes to Inflammatory Intestinal Epithelial Cells, Souphalone Luangsay, Lloyd H. Kasper, Nicolas Rachinel, and Laurie A. Minns
Interleukin-10 and Pathogenesis of Murine Ocular Toxoplasmosis, Fangli Lu, Shiguang Huang, and Lloyd H. Kasper
Copper Chelation Represses the Vascular Response to Injury, Lazar Mandinov, Anna Mandinova, Stanimir Kyurkchiev, Dobroslav Kyurkchiev, Ivan Kehayov, Vihren Kolev, Raffaella Soldi, Cinzia Bagala, Ebo D. de Muinck, Volkhard Lindner, Mark J. Post, and Michael Simons
sarU, a sarA Homolog, is Repressed by SarT and Regulates Virulence Genes in Staphylococcus aureus, Adhar C. Manna and Ambrose L. Cheung
Stoichiometry of site-specific protein phosphorylation estimated with phosphopeptide-specific antibodies, Cristinel P. Mîinea and Gustav E. Lienhard
Mammalian Erv46 Localizes to the Endoplasmic Reticulum–Golgi Intermediate Compartment and to Cis-Golgi Cisternae, Lelio Orci, Mariella Ravazzola, Gary J. Mack, Charles Barlowe, and Stefan Otte
Disulfide Bond Formation Involves a Quinhydrone-Type Charge–Transfer Complex, James Regeimbal, Stefan Gleiter, Bernard L. Trumpower, and Chang-Ang Yu
SarT Influences sarS Expression in Staphylococcus aureus, Katherine A. Schmidt, Adhar C. Manna, and Ambrose L. Cheung
Hierarchy of Protein Assembly at the Vertex Ring Domain for Yeast Vacuole Docking and Fusion, Li Wang, Alexey J. Merz, Kevin M. Collins, and William Wickner
Age, Gender, Biometry, Refractive Error, and the Anterior Chamber Angle among Alaskan Eskimos, Robert Wojciechowski, Nathan Congdon, William Anninger, and Aimee Teo Broman
Alginate is not a Significant Component of the Extracellular Polysaccharide Matrix of PA14 and PAO1 Pseudomonas Aeruginosa Biofilms, Daniel J. Wozniak, Timna J. O. Wyckoff, Melissa Starkey, Rebecca Keyser, Parastoo Azadi, George A. O'Toole, and Matthew R. Parsek
Nucleotide Excision Repair- and Polymerase Eta-Mediated Error-Prone Removal of Mitomycin C Interstrand Cross-Links, H. Zheng, X. Wang, A. J. Warren, R. J. Legerski, Rodney S. Nairn, Joshua W. Hamilton, and Lei Li
Submissions from 2002
Experimental Autoimmune Encephalitis and Inflammation in the Absence of Interleukin-12, Burkhard Becher, Brigit G. Durell, and Randolph J. Noelle
A Cycle Of Vam7p Release From And Ptdins 3-P–Dependent Rebinding to the Yeast Vacuole is Required for Homotypic Vacuole Fusion, Christine Boeddinghaus, Alexey J. Merz, Rico Laage, and Christian Ungermann
Type 4 Pilus Biogenesis and Type II-Mediated Protein Secretion by Vibrio cholerae Occur Independently of the TonB-Facilitated Proton Motive Force, Niranjan Bose, Shelley M. Payne, and Ronald K. Taylor
CD8+-T-Cell Immunity against Toxoplasma gondii Can Be Induced but Not Maintained in Mice Lacking Conventional CD4+ T Cells, Lori Casciotti, Kenneth H. Ely, Martha E. Williams, and Imtiaz A. Khan
Toxoplasma gondii Induces Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor Secretion by Human Fibroblasts: Implications for Neutrophil Apoptosis, Jacqueline Y. Channon, Kristin A. Miselis, Laurie A. Minns, Chaitali Dutta, and Lloyd H. Kasper
Remodeling of Organelle-Bound Actin is Required for Yeast Vacuole Fusion, Gary Eitzen, Li Wang, Naomi Thorngren, and William Wickner
Short-Circuiting Long-Lived Humoral Immunity by the Heightened Engagement of CD40, Loren D. Erickson, Brigit G. Durell, Laura A. Vogel, Brian P. Connor, Marilia Cascalho, Teruhito Yasui, Hitoshi Kikutani, and Randolph J. Noelle
Transcriptional Interference by Independently Regulated Genes Occurs in Any Relative Arrangement of the Genes and Is Influenced by Chromosomal Integration Position, Susan K. Eszterhas, Eric E. Bouhassira, David I. K. Martin, and Steven Fiering
The CD154/CD40 Interaction Required for Retrovirus-Induced Murine Immunodeficiency Syndrome Is Not Mediated by Upregulation of the CD80/CD86 Costimulatory Molecules, Kathy A. Green, W. James Cook, Arlene H. Sharpe, and William R. Green
Coupling of Termination, 3′ Processing, and mRNA Export, C. M. Hammell, Stefan Gross, Daniel Zenklusen, Catherine V. Heath, Francoise Stutz, Claire Moore, and C. N. Cole
Staphylococcus aureus agr and sarA Functions Are Required for Invasive Infection but Not Inflammatory Responses in the Lung, Geoffrey Heyer, Shahryar Saba, Robert Adamo, William Rush, Grace Soong, Ambrose Cheung, and Alice Prince
Fibroblast Growth Factor–Specific Modulation of Cellular Response by Syndecan-4, Arie Horowitz, Eugene Tkachenko, and Michael Simons
Mechanism of ToxT-Dependent Transcriptional Activation at the Vibrio cholerae tcpA Promoter, Robin R. Hulbert and Ronald K. Taylor
Searching for the Middle Ground: Mechanisms of Chromosome Alignment During Mitosis, Tarun M. Kapoor and Duane A. Compton
Treatment with Soluble Interleukin-15Ralpha Exacerbates Intracellular Parasitic Infection by Blocking the Development of Memory CD8+ T Cell Response, Imtiaz A. Khan, Magali Moretto, Xiao-qing Wei, Martha Williams, Joseph D. Schwartzman, and F Y. Liew
UBE1L is a Retinoid Target that Triggers PML/RARα Degradation and Apoptosis in Acute Promyelocytic Leukemia, Sutisak Kitareewan, Ian Pitha-Rowe, David Sekula, Christopher H. Lowrey, Michael J. Nemeth, Todd R. Golub, Sarah J. Freemantle, and Ethan Dmitrovsky
Increased Responsiveness of Hypoxic Endothelial Cells to FGF2 is Mediated by HIF-1 Alpha-Dependent Regulation of Enzymes Involved in Synthesis of Heparan Sulfate FGF2-Binding Sites, Jian Li, Nicholas W. Shworak, and Michael Simons
Identification of the Vibrio cholerae Enterobactin Receptors VctA and IrgA: IrgA Is Not Required for Virulence, Alexandra R. Mey, Elizabeth E. Wyckoff, Amanda G. Oglesby, Eva Rab, Ronald K. Taylor, and Shelley M. Payne
Short-lived and Long-lived Bone Marrow Plasma Cells Are Derived from a Novel Precursor Population, Brian P. O'Connor, Marilia Cascalho, and Randolph J. Noelle
Erv14p Directs a Transmembrane Secretory Protein into COPII-coated Transport Vesicles, Jacqueline Powers and Charles Barlowe
Genomic Analysis of Homotypic Vacuole Fusion, E Scott Seeley, Masashi Kato, Nathan Margolis, William Wickner, and Gary Eitzen
Neurospora Clock-Controlled Gene 9 (ccg-9) Encodes Trehalose Synthase: Circadian Regulation of Stress Responses and Development, Mari L. Shinohara, Alejandro Correa, Deborah Bell-Pedersen, Jay C. Dunlap, and Jennifer J. Loros
Clinical and Epidemiological Correlates of Genotypes within the Mycobacterium avium Complex Defined by Restriction and Sequence Analysis of hsp65, Sandra C. Smole, Fionnuala McAleese, Jutamas Ngampasutadol, C. Fordham von Reyn, and Robert D. Arbeit
Markers of apoptosis: Methods for elucidating the mechanism of apoptotic cell death from the nervous system, Paul G. Smyth, Stephen A. Berman, and Sherry Bursztajn
Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: Integration of complex signaling pathways for the recruitment of gene-specific transcription factors, Matthew P. Vincenti and Constance E. Brinckerhoff
Submissions from 2001
Evaluation of a Tetracycline-Inducible Promoter in Staphylococcus aureus In Vitro and In Vivo and Its Application in Demonstrating the Role of sigB in Microcolony Formation, B. T. Bateman, N. P. Donegan, T. M. Jarry, and M. Palma
SarS, a SarA Homolog Repressible by agr, Is an Activator of Protein A Synthesis in Staphylococcus aureus, Ambrose L. Cheung, Katherine Schmidt, Brian Bateman, and Adhar C. Manna
The Mannose-Sensitive Hemagglutinin of Vibrio cholerae Promotes Adherence to Zooplankton, Deborah A. Chiavelli, Jane W. Marsh, and Ronald K. Taylor
Circadian Clock-Specific Roles for the Light Response Protein WHITE COLLAR-2, Michael A. Collett, Jay C. Dunlap, and Jennifer J. Loros
The Type 2 Iodothyronine Deiodinase is Essential for Adaptive Thermogenesis in Brown Adipose Tissue, Lucia A. de Jesus, Suzy D. Carvalho, Mirian O. Ribeiro, Mark Schneider, Sung-Woo Kim, John W. Harney, P. Reed Larsen, and Antonio C. Bianco
Nuclear Export of 60S Ribosomal Subunits Depends on Xpo1p and Requires a Nuclear Export Sequence-Containing Factor, Nmd3p, That Associates with the Large Subunit Protein Rpl10p, Olivier Gadal, Daniela Strau, Jacques Kessl, and Bernard Trumpower
Chromosome Movement in Mitosis Requires Microtubule Anchorage at Spindle Poles, Michael B. Gordon, Louisa Howard, and Duane A. Compton
Characterization of the CD154-Positive and CD40-Positive Cellular Subsets Required for Pathogenesis in Retrovirus-Induced Murine Immunodeficiency, Kathy A. Green, Randolph J. Noelle, Brigit G. Durell, and William R. Green
Patient Choice Modules for Summaries of Clinical Effectiveness: A Proposal, Margaret Holmes-Rovner, Hilary Llewellyn-Thomas, Vikki Entwistle, and Angela Coulter
Comparison of Two Azithromycin Distribution Strategies for Controlling Trachoma in Nepal, Susan Osaki Holm, Hem C. Jha, Ramesh C. Bhatta, J.S. P. Chaudhary, B. B. Thapa, Dale Davis, Ram Prasad Pokhrel, Miao Yinghui, Michael Zegans, Julius Schachter, Kevin D. Frick, Lisa Tapert, and Thomas M. Leitman
Arsenic Alters the Function of the Glucocorticoid Receptor as a Transcription Factor, Ronald C. Kaltreider, Alisa M. Davis, Jean P. Lariviere, and Joshua W. Hamilton
Ups and Downs of Mucosal Cellular Immunity against Protozoan Parasites, Lloyd H. Kasper and Dominique Buzoni-Gatel
The Chromokinesin Kid is Necessary for Chromosome Arm Orientation and Oscillation, but Not Congression, on Mitotic Spindles, Aime A. Levesque and Duane A. Compton
Crystal Structure of the SarR Protein from Staphylococcus aureus, Yingfang Liu, Adhar Manna, Ronggui Li, Wesley E. Martin, Robert C. Murphy, Ambrose L. Cheung, and Gongyi Zhang
Analysis of Mitotic Microtubule-Associated Proteins Using Mass Spectrometry Identifies Astrin, a Spindle-Associated Protein, Gary J. Mack and Duane A. Compton
Characterization of sarR, a Modulator of sar Expression in Staphylococcus aureus, Adhar Manna and Ambrose L. Cheung
Immune Response Genes Modulate Serologic Responses to Vibrio cholerae TcpA Pilin Peptides, Michael D. Meeks, Terri K. Wade, Ronald K. Taylor, and William F. Wade
IL-1 Induces Collagenase-3 (MMP-13) Promoter Activity in Stably Transfected Chondrocytic Cells: Requirement for Runx-2 and Activation by p38 MAPK and JNK Pathways, John A. Mengshol, Matthew P. Vincenti, and Constance E. Brinckerhoff
A PDZ-Binding Motif is Essential but Not Sufficient to Localize the C Terminus of CFTR to the Apical Membrane, Michal I. Milewski, John E. Mickle, John K. Forrest, Diane M. Stafford, Bryan D. Moyer, Jie Cheng, William B. Guggino, Bruce A. Stanton, and Garry R. Cutting
